Removing exogenous information using pedigree data
نویسندگان
چکیده
منابع مشابه
IPED: Inheritance Path Based Pedigree Reconstruction Algorithm Using Genotype Data
The problem of inference of family trees, or pedigree reconstruction, for a group of individuals is a fundamental problem in genetics. Various methods have been proposed to automate the process of pedigree reconstruction given the genotypes or haplotypes of a set of individuals. Current methods, unfortunately, are very time-consuming and inaccurate for complicated pedigrees, such as pedigrees w...
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We developed a general framework for family-based imputation using single-nucleotide polymorphism data and sequence data distributed by Genetic Analysis Workshop 18. By using PedIBD, we first inferred haplotypes and inheritance patterns of each family from SNP data. Then new variants in unsequenced family members can be obtained from sequenced relatives through their shared haplotypes. We then ...
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Reliable population estimates are an important aspect of sustainable wildlife management and conservation but can be difficult to obtain for rare and elusive species. Here, we test a new census method based on pedigree reconstruction recently developed by Creel and Rosenblatt (2013). Using a panel of 96 single-nucleotide polymorphisms (SNPs), we genotyped fecal samples from two Swedish brown be...
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The harmful effects of inbreeding can be reduced if deleterious recessive alleles were removed (purged) by selection against homozygotes in earlier generations. If only a few generations are involved, purging is due almost entirely to recessive alleles that reduce fitness to near zero. In this case the amount of purging and allele frequency change can be inferred approximately from pedigree dat...
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The generation of too much information prohibits eecient resolution proof search in classical logics. Hence subsumption is used to discard redundant information and strategies have been developed to guide the proof search avoiding irrelevant information. The extension of the resolution method to temporal logics, for example that by Fisher for propositional linear-time temporal logics, further m...
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ژورنال
عنوان ژورنال: Conservation Genetics
سال: 2011
ISSN: 1566-0621,1572-9737
DOI: 10.1007/s10592-011-0255-4